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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight-loss in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it one should err to the side of caution and allow FDA do its job and demand some research be done so that the public is aware of the side effects and hazards of the medications before we take them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on the medications.

    Researchers found out that participants using this drug for a year, lost excess weight within one month and have kept the weight off through the entire 56 weeks with the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which might be made up of several active ingredient, which may make them far better and safer.

    Combo-pilling may be the newest fad or better yet the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that as of right now there aren't any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA.

    Seizures are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heart rate, and shouldn't be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high blood pressure, and also by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients towards the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

    An independent report published by Gant Daily in April also stated that naltrexone also works best for kleptomaniacs and gambling addicts, also. Citing research from your University of Minnesota School of Medicine, Gant Daily reported that this drug conditions kleptomaniacs and chronic gamblers just as with alcohol and opioid addicts'by blocking the end results of endorphins, that your brain releases when experiencing craving or compulsions.